Clinical Pharmacological Study of Mizolastine (MKC-431).

Hypersensitivity reaction to mizolastine: study of cross reactions.

A 26-year-old male suffering from acute rhinitis took the first dose of Zolistan (mizolastine, 10 mg), orally, and 15 minutes later he developed intense generalized pruritus, cutaneous rash, oropharyngeal pruritus, edema on his face, difficulty in swallowing, and mild dyspnea. He was treated with methylprednisolone and epinephrine and improved within 30 minutes. The patient had not taken mizola...

inductive effect of palatal connective tissue on alveolar mocosa after subepithelial connective tissue graft clinical & histologic study

چکیده ندارد.

Clinical Trial and Pharmacological Study of Compound 1029. ("vatensol").

Phase I clinical and pharmacological study of merbarone.

Merbarone, a nonsedating derivative of thiobarbituric acid, has demonstrated excellent activity against certain murine tumors, including L1210 and P388 leukemias, B16 melanoma, and M5076 sarcoma. Preclinical studies suggested that the antitumor effects of this drug were schedule dependent, since repeated dosing increased killing of tumor cells when compared to intermittent injections. We have c...

Phase I Clinical and Pharmacological Study of Merbarone1

Merbarone, a nonsedating derivative of thiobarbituric acid, has dem onstrated excellent activity against certain murine tumors, including LI210 and P388 leukemias, B16 melanoma, and M5076 sarcoma, froclinical studies suggested that the antitumor effects of this drug were schedule dependent, since repeated dosing increased killing of tumor cells when compared to intermittent injections. We have ...